EPIDEMIOLOGY AND RISK FACTORS OF WARM AND COLD AUTOIMMUNE HEMOLYTIC ANEMIA

Even though clinical features in autoimmune haemolytic anaemia vary according to the type of AIHA, anaemic syndrome stays common for most cases. A positive Coombs test or direct anti-globulin developed 1945 by Coombs, Mourant and Race, is deciding factor AIHA diagnosis. Since immunologic mechanisms causing erythrocyte destruction between AIHAs, treatment also different. Empirical approach with glucocorticoids main overall, but less effective CAD. However, current medical literature still gaps concerning management, presentation diagnosis different types altogether.